12 results
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Antinuclear Antibody ... and Cytoplasmic Patterns ... Nuclear Patterns ... • Homogeneous pattern ... ) • Speckled pattern
Antinuclear Antibody Testing - Nuclear Patterns
Homogeneous pattern: 
 • SLE, SSc, AIH, JIA
 • dsDNA, chromatin,
Antinuclear Antibody ... Testing - Nuclear Patterns ... Homogeneous pattern ... ) Speckled pattern ... Ku Centromere pattern
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... • Nucleolar: Diffuse ... Kumfer @AnnKumfer #Antinuclear ... Antibodies #ANA #patterns ... #rheumatology #
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
serial dilution, a pattern ... significant • Pattern ... : The ANA patterns ... not specific ANA Patterns ... Antibodies #ANA #patterns
Inflammatory Myopathies
Dermatomyositis
 • Onset: Subacute
 • Pattern: Proximal
 • CK: Up to 50X ULN
 • Autoantibodies:
: Subacute • Pattern ... : Subacute • Pattern ... or subacute • Pattern ... Insidious/slow • Pattern ... table
Differential diagnosis
The table summarizes the most common diseases, that present with consolidation.
Chronic diseases are indicated in
diagnosis The table ... to look at the pattern ... more than one pattern ... lobar pneumonia caused ... #Differential #Table
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm

DIFFUSE
Scarring - Irreversible-biopsy required
 • Lupus
Differential Diagnosis Algorithm ... planopilaris Pattern ... HairLoss #Alopecia #dermatology ... Differential #Diagnosis #Algorithm ... #causes
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
Focal Hair Loss Pattern ... Hair Loss Pattern ... Alopecia: - Pattern ... alopecia in men (male pattern ... loss), Female pattern
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... lymphadenopathy more diffuse ... involvement, irregular pattern ... pathophysiology #Hematology ... #differential #algorithm
Diffuse Hair Loss (Alopecia) - Differential Diagnosis Algorithm

Scarring - Irreversible-biopsy required
 • Lupus erythematosus
 • Lichen
Diffuse Hair Loss ... Differential Diagnosis Algorithm ... planopilaris Pattern ... HairLoss #Alopecia #dermatology ... #causes