18 results
Lab patterns seen in Inborn Errors of Metabolism

A table of lab values compiled from UpToDate and
Lab patterns seen ... Metabolism A table ... of lab values compiled ... metabolicemergency-pathophysiology-differential-pediatrics-metabolism-algorithm-diagnosis ... #Table #NICU #Genetics
A schema of the pathophysiology of the inborn errors of metabolism, excluding complex storage diseases. Helps
See the lab values ... table for supplemental ... , UpToDate #Pediatrics ... Pathophysiology #Diagnosis #Algorithm ... #Table #IEM #NICU
Fever of Unknown Origin (FUO) - Further Workup

 • CNS symptoms? Get an LP and imaging
FUO) - Further Workup ... Returning Traveler’ algorithm ... artery biopsy • Lab ... values supporting ... hematologic malignancies
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Causes of Extravascular ... Differential Diagnosis Algorithm ... Drug-induced AIHA - Abnormal ... Prosthetic heart valves ... #Causes #Hematology
Erythrocytosis - Polycythemia Differential Diagnosis Algorithm

Elevated Hemoglobin:
 • Males: Hb > 16.5 g/dL/HCT ≥ 49%
 •
Differential Diagnosis Algorithm ... Hemoglobin: • Males ... Polycythemia - Acquired Causes ... ), TEMPI (VEGF normal ... #hematology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
FLAGS - In all cases ... splenomegaly, abnormal ... cell disease Rheumatology ... #Limping #NWB #Algorithm ... #Child #Peds #Pediatrics
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
activity - A low value ... If the value is ... levels - Usually normal ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
CRP - Usually normal ... • Immunologic Workup ... Discontinuation of causal ... sle #comparison #table ... #rheumatology #
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Differential Diagnosis Algorithm ... that a one-off value ... Better call hematology ... exogenous, EPO levels: normal ... #workup #hematology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
intralobular bile ducts causes ... wasting PBC Labs ... • ALT & AST normal ... cholangitis #diagnosis #workup ... #hepatology