11 results
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... sedimentation rate + Normal ... Skin Disease Classification ... Cytopenias • Cardiac valve ... : • Symptoms limited
Rheumatoid Arthritis - 2020 ACR-EULAR Classification
≥ 6 of 10 points = definite RA
Joint Involvement:
Rheumatoid Arthritis ... 2020 ACR-EULAR Classification ... joint) - 5 points Serology ... points Duration of symptoms ... #Rheumatoid #Arthritis
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
(SLE) General: ... Butterfly rash, Vasculitis ... of hip (rare), Arthritis ... Endocarditis, Aortic valve ... erythematosus #signs #symptoms
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Non-scarring alopecia, Oral ... • Arthritis domain ... least 2 joints • Neurologic ... #Criteria #SLE
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
such as systemic lupus ... Presentation - Systemic Symptoms ... retinopathy Lab ... , and SLE) • Urinalysis ... #rheumatology #classification
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... meningitis), MCC CNS symptoms ... aphthae : SLE, ... : SLE, Reactive ... management #signs #symptoms
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
diseases: - 10% SLE ... Labs/Diagnosis: ... (e.g. systemic lupus ... erythematosus (SLE ... diagnosis #types #classification
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
diseases, such as SLE ... Presentation: Systemic Symptoms ... affects the skin, neurologic ... • Progressive symptoms ... cognitive impairment, neurologic
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic inflammatory vasculitis ... with systemic, neurologic ... or sed rate): Value ... 50 in GCA, but normal ... values increase
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
including systemic lupus ... erythematosus (SLE ... ANCA-associated vasculitis ... plasma cells Labs ... phosphatase - Normal