18 results
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
of Bleeding / Bruising ... - Differential Diagnosis ... Algorithm Thrombocytopenia ... Sequestration Disordered ... #Hematology
Warm vs Cold Autoimmune Hemolytic Anemia
Warm Autoimmune Hemolytic Anemia:
 • Mechanism: IgG and Complement-mediated
 • Etiology:
Warm vs Cold Autoimmune ... Lymphoproliferative disorder ... , Autoimmune disorder ... #Anemia #hematology ... #diagnosis #comparison
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... intravascular coagulation ... (e.g. primary cold ... lymphoproliferative disorders ... #hematology #anemia
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
- Differential Diagnosis ... Algorithm Extravascular ... Warm AIHA • Cold ... #Algorithm #Causes ... #Hematology
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
#Differential #Diagnosis ... #Algorithm #Causes ... #Hematology #coagulation ... #disorders
Pediatric Neutropenia Workup Algorithm

DOI: 10.1111/ijlh.13210

#Neutropenia #Workup #Algorithm #diagnosis #hematology #Pediatrics #peds
Pediatric Neutropenia ... Workup Algorithm ... Neutropenia #Workup #Algorithm ... #diagnosis #hematology ... #Pediatrics #peds
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential Diagnosis ... Algorithm • Sickle ... Agglutination - Cold ... Consider RBC membrane disorder ... #hematology #testing
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... , coagulation disorders ... DIC/TTP/HUS - Hemolytic ... #Differential #Diagnosis ... #hematology #rheumatology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
sweats, pallor, bruising ... neurology, back pain Haematology ... cell disease Rheumatology ... Pathway #Child #Peds ... #Pediatrics #Diagnosis
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
lymphoproliferative disorder ... infection, autoimmune disorder ... Diagnosis: • hemolytic ... Monoclonal IgM Includes Disorders ... #anemia #hematology