12 results
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Chronic - ongoing ↑ LFTs ... or symptoms of liver ... Idiosyncratic #differential ... gastroenterology #algorithm ... gastroenterology #hepatology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... / Bruising - Differential ... Diagnosis Algorithm ... Iatrogenic) • Liver ... #Causes #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential ... - History of bleeding ... gastric bypass), LFT ... (liver disease) ... #Workup #hematology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... for alternative causes ... Hepatic vascular disorder ... Injury #Diagnosis #Algorithm ... #hepatology
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
Causes of Prolonged ... #PPT #PT #INR #Differential ... #Diagnosis #Algorithm ... #Causes #Hematology ... #coagulation #disorders
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Causes of Anemia ... Volume (MCV) - Differential ... Diagnosis Algorithm ... 80-100 fL) • Bleeding ... #Causes #Hematology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... - Differential ... • Others #LFTs ... #Hepatology #LiverEnzymes ... #Causes
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Diagnosis Algorithm ... Vascular Causes ... RBC (hemolysis, bleeding ... #hepatology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Volume (MCV) - Differential ... Diagnosis Algorithm ... • Small Bowel Disorder ... #Causes #Hematology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... RBC (hemolysis, bleeding ... chemistry #diagnosis #differential ... #Hepatology #transaminitis ... #LFTs #RValue #