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oncology differential mds myelodysplastic alopecia anemia barre chronic diffuse essential et focal guillain guillainbarre hairloss leukemia lymphocytic myelodysplasia neutropenia rheumatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Summary myelo ( ... dys- (abnormal) -plastic ... old, ~10,000 new cases ... #Management #treatment ... #hematology #oncology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic ... ITP • SLE • CLL ... Non-lmmune: • HELLP Syndrome ... #Algorithm #Causes ... #Hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphocytic Leukemia - Summary ... Diagnosis: • ... aplasia • ITP ... microglobulin Treatment ... workup #oncology #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... and petechiae Causes ... anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
Algorithm DIFFUSE ... • Loose anagen syndrome ... Follicularis • Aplasia ... HairLoss #Alopecia #dermatology ... #Algorithm #causes
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Out Secondary Causes ... • Anemia • Aplastic ... factor (GCSF) treatments ... marrow studies Treatment ... #diagnosis #hematology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
- Differential Diagnosis ... hypertension and/or drug treatment ... Chediak-Higashi syndrome ... aplasia DOI: 10.1111 ... #causes #hematology
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
- Summary Acute ... Epidemiology: • 1-2 cases ... Guillain-Barre Diagnosis ... #diagnosis #management ... #treatment #neurology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
SAPHO Syndrome Summary ... Rule out other causes ... and lower jaw Treatment ... diagnosis #management ... #Dermatology
Essential Thrombocythemia (ET) ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
PV, MDS, CML) Treatment ... • Treatment algorithms ... Thrombocythemia #ET #hematology ... #diagnosis #management ... #hematology
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