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hematology algorithm causes mcv oncology atlas classification deficiency management pancytopenia pathophysiology rbc agglutinin ascorbicacid bloodcell calculation cold dehydrogenase disease elevated
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Blood Cell (RBC) Morphology ... Vitamin B12 or Folate ... BloodCell #RBC #Morphology ... #differential # ... diagnosis #hematology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
deficiency • Fanconi’s anemia ... Antibody-mediated hemolysis ... Nutritional ... Vitamin B12 • Folate ... #Diagnosis #Hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
- Differential ... Diagnosis Framework ... , CKD • Hemolytic ... Megaloblastic: Folate ... #Diagnosis #hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Blood Cell (RBC) Morphology ... spherocytosis, Hemolytic ... #Atlas #key #diagnosis ... #differential # ... hematology
Clinically Important Vitamins and Vitamin Deficiency States Fat-soluble Vitamins: • Vitamin A - Xerophthalmia, night blindness,
• Vitamin E - Haemolytic ... paraesthesiae • Folate ... Vitamins #Deficiency #differential ... #diagnosis #signs ... #symptoms #nutrition
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
Diagnosis Algorithm ... Toxins • Aplastic Anemia ... Myelodysplasia Nutritional ... deficiency: • B12/folate ... #Causes #Hematology
Etiologies of Folate Deficiency • Decreased dietary intake - uncommon in this era • Increased requirements
pregnant have hemolytic ... anemia, or psoriasis ... deficiency #FolicAcid #differential ... #diagnosis #hematology ... #nutrition
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Diagnosis Algorithm ... other reproducible morphologic ... #Anemia #Differential
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... Diagnosis Algorithm ... • Bleeding • Hemolysis ... Deficiency • Folate ... #Causes #Hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
, Vitamin B12, Folate ... Microangiopathic hemolytic ... Production #Index #hematology ... #anemia #differential ... #diagnosis #calculation
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