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oncology causes leukemia lymphocytic workup abg acidbase agglutinin apml arteritis base blood bloodgas classification cold cvid differentiation disease erythematosus essential
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Diagnosis Algorithm ... - CD7, CD3 Chronic ... • Lymphoid (CLL ... #hematology #Markers ... Diagnosis #Algorithm
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Diagnosis Secondary ... malignancies • Anemia ... inflammatory disorders ... Myelodysplastic syndrome ... #hematology #secondary
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
: • Most common ... Lymphadenopathy • Fevers ... Physical Exam/Signs ... • Neutropenia, anemia ... workup #oncology #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Agglutinin Syndrome ... symptoms - most common ... younger pts) Differential ... Symptoms: High fevers ... #hematology #diagnosis
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
Neutropenia - Differential ... Diagnosis Neonate ... Chediak-Higashi syndrome ... Megaloblastic anemia-rare ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... leukemia in adults • Disorder ... ) B symptoms → fevers ... Leukemia #oncology #hematology ... #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Most common cytopenia ... DDX: Rule Out Secondary ... Marrow Failure • Chronic ... vitamin B12 or folic acid ... #diagnosis #hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... infection risk secondary ... autoimmune hemolytic anemia ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Acid Base Disorders - Blood Gas Interpretation Steps for Blood Gas Interpretation: 1. Acidemia or Alkalemia? 2.
Acid Base Disorders ... (AG) = {Na - (Cl ... L L-lactate (common ... D-lactate (short bowel syndrome ... Anxiety, pain, fever
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... • Induce blast cell ... : fever, myalgias ... initiation • Differential ... #management #hematology
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