24 results
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
immunophenotype Clinical ... Complications: 1) Infection ... chemotherapy for low-risk disease ... marrow failure with anemia ... hemeonc #diagnosis #management
Causes of Apparent Life Threatening Event (ALTE) - Differential Diagnosis Algorithm
Cardiac:
 • Congenital Heart Disease
 •
Causes of Apparent ... Congenital Heart Disease ... Metabolism • Reye's Syndrome ... Breathing • Apnea of Infancy ... #Peds #Pediatrics
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... -> AML: Blast crises ... develop leukostasis syndrome ... - infiltrates (anemia ... • Tumor lysis syndrome
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... Granulomatous lymphocytic ... autoimmune hemolytic anemia ... DDX - Other causes ... : • Nephrotic syndrome
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... with no early symptoms ... weeks without infection ... cells can indicate disease ... • Neutropenia, anemia
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Clinical Presentation ... of anemia include ... younger pts) Differential ... #hematology #diagnosis
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... and petechiae Causes ... Idiopathic • Infections ... • Improve the symptoms ... #diagnosis #management
Causes of Hypotonic Infant (Floppy Newborn) - Differential Diagnosis Algorithm
Central Nervous System - Decreased LOC, Axial
Causes of Hypotonic ... Infant (Floppy ... Hemorrhage • CNS Infection ... Other Congenital Syndromes ... #Peds #Pediatrics
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
than 1500 and clinical ... eosinophilia Secondary Causes ... hypersensitivity - Infection ... Myeloproliferative HES - Lymphocytic ... #differential #
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... frequently affects infants ... age, however the disease ... HLH signs and symptoms