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syndrome oncology blood hemophagocytic lymphohistiocytosis product reactions thrombocytosis activation apml behcet calcium causes child chronic classification cll cppd deposition dermatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Diagnosis Algorithm ... → Refer to hematology ... Rebound effect from treatment ... #Diagnosis #Algorithm ... #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Diagnosis Algorithm ... Myelofibrosis Infectious ... effect following treatment ... #Diagnosis #Algorithm ... #Causes #Hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Autoimmune diseases ... Adult-onset Still disease ... Unknown cause Treatment ... #management #treatment ... #summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
age, however the disease ... : • Infection ... agent are the main ... #management #treatment ... #hematology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY RED FLAGS - In all cases there are specific markers which
Haematology - ... Rheumatology ... #Limping #NWB #Algorithm ... Pathway #Child #Peds ... #Pediatrics #Diagnosis
Kawasaki Disease (KD) - Diagnosis and Management Summary Kawasaki Disease (KD) is the most common vasculitis of
Summary Kawasaki ... cæxist with other infections ... KD #vasculitis #rheumatology ... #pediatrics #diagnossi ... #management #treatment
Polycythemia Vera (PV) - Diagnosis and Management Summary Diagnostic Criteria: • Elevated hemoglobin and/or hematocrit AND •
Summary Diagnostic ... • Treatment algorithms ... von Willebrand disease ... #Management #Summary ... #treatment #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
SLE], AOSD) • Infection ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Leukemia (CLL) - Summary ... Complications: 1) Infection ... chemotherapy for low-risk disease ... Leukemia #oncology #hematology ... #management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... effusions, weight gain ... initiation • Differential ... Diagnosis: Infection ... #management #hematology
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