18 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Metastatic cancer, Lymphoma ... #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
dys- (abnormal) -plastic ... cytopenias (usually anemia ... risk-stratification • Risks: infection ... #Management #treatment ... #hematology #oncology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Alcohol-induced pain ... : Pain in involved ... NonHodgkins #comparison #oncology ... #diagnosis #differential ... #hematology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
and Management ... disorders (e.g. lymphoma ... thrombocythemia), Autoimmune disease ... #Management #treatment ... #hematology #differential
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
Chronic kidney disease ... marrow failure: Aplastic ... • "Hospital-acquired ... Production #Index #hematology ... #anemia #differential
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... anemia Treatment ... #Anemia #oncology ... #hematology #diagnosis
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Nodules • Lymphoid ... severe community-acquired ... autoimmune hemolytic anemia ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
autoimmune disorder or lymphoid ... - Monoclonal - Lymphoid ... younger pts) Differential ... chills, flank pain ... #hematology #diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Complications: 1) Infection ... to large cell lymphoma ... chemotherapy for low-risk disease ... #hematology #hemeonc ... #diagnosis #management
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
weeks without infection ... • Neutropenia, anemia ... Pure red cell aplasia ... #workup #oncology ... #hematology