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chronic leukemia lymphocytic myelodysplastic agglutinin algorithm causes classification hemeonc hemolytic hodgkins myelodysplasia neutropenia platelets syndrome syndromes thrombocytosis transfusion transfusions workup
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... : Acute blood loss ... hemolysis, deficiency anemia ... Metastatic cancer, Lymphoma ... #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
cytopenias (usually anemia ... risk-stratification • Risks: infection ... #Diagnosis #Management ... #treatment #hematology ... #oncology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
symptoms - most common ... anemia • Cold ... younger pts) Differential ... chills, flank pain ... #hematology #diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
: • Most common ... weeks without infection ... aplasia • ITP ... #workup #oncology ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... anemia Treatment ... #Anemia #oncology ... #hematology #diagnosis
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
Infant/child: - Infection-common ... ambulatory patients - Infections-common ... including white blood ... cell aplasia DOI ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Complications: 1) Infection ... lymphoma (Richter ... chemotherapy for low-risk disease ... #hematology #hemeonc ... #diagnosis #management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... • Pain in LN ... Treatment • Early ... #hematology #oncology ... #management
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... : Fever, flank pain ... Blood products contain ... #diagnosis #management ... #hematology #reactions
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
: Fever, flank pain ... due to marrow aplasia ... Blood products contain ... #diagnosis #management ... #hematology #reactions
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