22 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... : Acute blood loss ... hemolysis, deficiency anemia ... Metastatic cancer, Lymphoma ... #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
dys- (abnormal) -plastic ... cytopenias (usually anemia ... risk-stratification • Risks: infection ... #Management #treatment ... #hematology #oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
: • Most common ... weeks without infection ... aplasia • ITP ... #workup #oncology ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... - infiltrates (anemia ... • Tumor lysis syndrome ... #Hematology #Oncology ... #Diagnosis
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... anemia Treatment ... #Anemia #oncology ... #hematology #diagnosis
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... symptoms - most common ... younger pts) Differential ... chills, flank pain ... #hematology #diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Complications: 1) Infection ... lymphoma (Richter ... chemotherapy for low-risk disease ... #hematology #hemeonc ... #diagnosis #management
Causes of Neutropenia - Differential Diagnosis
Neonate:
 - Infection - by far the most common cause
 -
Infant/child: - Infection-common ... ambulatory patients - Infections-common ... including white blood ... cell aplasia DOI ... #hematology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... • Nodules • Lymphoid ... autoimmune hemolytic anemia ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... • Pain in LN ... (NSHL) - (most common ... #hematology #oncology ... #management