19 results
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
Differential Diagnosis ... Reactive: • Anemia ... /blood loss (Fe ... Diagnosis #causes ... #Platelets #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... Myelogenous Leukemia ... Myelofibrosis Infectious ... Iron deficiency anemia ... #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... : Acute blood loss ... , Vasculitides, ... : Chronic infections ... #hematology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Illness Script Signs ... and symptoms: ... • Recurrent infections ... #diagnosis #management ... #treatment #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... extramedullary disease ... , bleeding, infections ... #Hematology #Oncology ... #Diagnosis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
procedures - Infection ... pylori test (GI symptoms ... changes), high MCV anemia ... #Diagnosis #Causes ... #Workup #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Chronic Lymphocytic ... Complications: 1) Infection ... chemotherapy for low-risk disease ... #oncology #hematology ... #management
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... younger pts) Differential ... sensitize red blood ... chills, flank pain ... #hematology #diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
with no early symptoms ... weeks without infection ... Physical Exam/Signs ... • Neutropenia, anemia ... #oncology #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... Marrow Failure • Chronic ... Myeloproliferative Disease ... count with differential ... #hematology #oncology