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algorithm management oncology apml causes disorders eosinophil eosinophils hes monoclonal paraproteinemias platelets thrombocytosis vasculitides
Causes of Eosinophilia - Differential Diagnosis Bugs: - Fungus (aspergillosis) - Viral (HIV) - Ectoparasites (scabies, myiasis)
- Differential ... Asthma Tugs (vasculitis ... Leukemia - Primary Hypereosinophilic ... Syndrome - Chronic ... #hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
/hypereosinophilia ... drug reaction, infection ... glucocorticoid treatment ... Disorders #Algorithm #Differential ... #diagnosis #hematology
Hypereosinophilia Syndrome (HES) - Diagnosis and Management Definition: An absolute eosinophil count (AEC) greater than 1500 and
Hypereosinophilia ... Syndrome (HES) ... hypersensitivity - Infection ... #eosinophilia #diagnosis ... #hematology #differential
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Rebound effect from treatment ... , Vasculitides, ... Kawasaki, Nephrotic syndrome ... #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation ... Syndrome in APML ... initiation • Differential ... Diagnosis: Infection ... #hematology #oncology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
• EGPA: - Eosinophilia ... to exclude are infections ... differential #diagnosis ... #rheumatology # ... classification
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Autoimmunity: • -MM/WM: Vasculitis ... Episodic angioedema+eosinophilia ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
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