11 results
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Diagnosis Algorithm ... Hypersplenism, Infection ... #Anemias #Differential ... #Diagnosis #Algorithm ... #hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... glucocorticoid treatment ... #Differential # ... diagnosis #hematology ... #eosinophilia
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Diagnosis Algorithm ... → Refer to hematology ... , deficiency anemia ... #Diagnosis #Algorithm ... #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Diagnosis Algorithm ... Myelofibrosis Infectious ... Iron deficiency anemia ... #Diagnosis #Algorithm ... #Causes #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Diagnosis Algorithm ... #Anemia #Differential ... #Diagnosis #Algorithm ... #workup #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
/fevers • Thrombocytopenia ... - Hepatitis, eosinophilic ... Treatment: ... #oncology #hematology ... #diagnosis #management
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Coombs (-) hemolytic ... anemia due to cold ... Episodic angioedema+eosinophilia ... Paraproteinemias #Hematology ... #Diagnosis #Oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
weeks without infection ... • Neutropenia, anemia ... , thrombocytopenia ... #workup #oncology ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
• (Peripheral eosinophilia ... - infiltrates (anemia ... , thrombocytopenia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Workup: • Complete ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology