11 results
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
interactions) Cancer-treatment ... cytochrome p450 CYP3A4 ... #Chemotherapy #Oncology ... #Interactions #Table ... #Pharmacology
Pericarditis can be seen on EKG with diffuse ST elevations without reciprocal changes along with diffuse
Pericarditis can ... First line treatment ... for pericarditis ... #Cardiology #Diagnosis ... #Signs #Symptoms
PDE5 inhibitors are usually the drugs of first choice for erectile dysfunction.

PDE5 inhibitors enhance an erection that is
alpha blockers and CYP3A4 ... #pharmacology #comparison ... #treatment #medications ... dosing #drugs #table
Clozapine Toxicology
Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
patients who have treatment-resistant ... effect on negative symptoms ... in the liver by CYP1A2 ... major), CYP2D6 and CYP3A4 ... Toxicity #Diagnosis #Pharmacology
Immune Checkpoint Inhibitor Toxicity

Main Toxicities: Colitis,  
Pneumonitis, Skin adverse events, Endocrine dysfunction, 
Hepatitis,  
Myocarditis,
Incidence, Symptoms ... Complications and Treatment ... #SideEffects #Table ... #Diagnosis #Pharmacology ... #Oncology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
management #algorithm #pharmacology ... #treatment #medications ... #table #pharmacotherapy ... #decisionaid #cardiology
Summary of meta-analysis of pharmacotherapy trials in BPD
https://www.cochrane.org/CD005652/BEHAV_psychological-therapies-borderline-personality-disorder
Meta-analyses of RCTs were undertaken for the following outcomes:
outcomes: BPD symptoms ... with ‘treatment ... summarised in Tables ... EBM #Management #Pharmacology ... Effectiveness #Table
Acute Recurrent Pericarditis
= recurrence of Acute Pericarditis (AP) after free interval >4-6 weeks without symptoms, >1/4
weeks without symptoms ... Myopericarditis, Systemic symptoms ... manifestations, TREATMENT ... diagnosis #management #treatment ... #rheumatology #cardiology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
& Dry) is the treatment ... & Dry” is the treatment ... algorithm #management #cardiology ... #treatment #table ... icu #clinical #pharmacology
Management of Immune Checkpoint Inhibitor (ICI) Induced Cardiotoxicity
Problem - Immune checkpoint inhibitors (ICIs) are associated with
serious arrhythmias, pericarditis ... abatacept for the treatment ... Cardiotoxicity #cardiology ... #oncology #management ... #treatment