15 results
Nitrofurantoin Toxicology
Serious Adverse Effects:
Hemolysis in patients with G6PD-deficiency
Peripheral neuropathy
Hepatitis
Pulmonary toxicity
Nephritis

By Dr. Kathryn Watson @Kat_Watson

#Nitrofurantoin #Macrobid #Toxicity
Nitrofurantoin Toxicology ... G6PD-deficiency Peripheral ... neuropathy Hepatitis Pulmonary ... #Toxicology #Pharmacology ... #Diagnosis
Amiodarone Toxicity and Monitoring

Tremor Ataxia 
Ocular neuritis 
Corneal Microdeposits 
Bradycardia 
Pulmonary fibrosis 
Hepatotoxicity 
Blue-gray skin
Amiodarone Toxicity ... Bradycardia Pulmonary ... Hypothyroid Peripheral ... SideEffects #Adverse #Diagnosis ... #Management #Pharmacology
Testicular Cancer - Treatment Related Toxicities

Bleomycin, Cisplatin, Etoposide, lfosfamide
Tinnitus & Hearing Loss
Neurotoxicity
Pulmonary Fibrosis
Hypotension
Nephrotoxicity
Skin Hyperpigmentation
Hemorrhagic Cystitis
Myelosuppression
Peripheral Neuropathy

Ashley
Testicular Cancer - Treatment ... Neurotoxicity Pulmonary ... #chemotherapy #toxicity ... #toxicology #Toxicities ... #pharmacology #
Salicylate Toxicity - Diagnosis and Management

Consider if:
1) Patient is hot and altered
2) You see tachypnea with
Salicylate Toxicity ... - Diagnosis and ... , Diaphoresis, Pulmonary ... #Toxicology #diagnosis ... #management #Treatment
Salicylate Poisoning - Toxicology

Acute toxicity = vomiting, tachypnea, tinnitus, diaphoresis, and lethargy. This may progress to
Salicylate Poisoning - Toxicology ... hyperthermia, coma, and pulmonary ... Cerebral and pulmonary ... #Toxicology #Pharmacology ... #Diagnosis #Management
Clozapine Toxicology
Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
Clozapine Toxicology ... patients who have treatment-resistant ... #Clozapine #Toxicology ... #Toxicity #Diagnosis ... #Pharmacology
Endocarditis checklist
Initial evaluation
 • Peripheral blood cultures (three sets at three different sites)
 • Additional culture
evaluation • Peripheral ... endocarditis w/ septic pulmonary ... spleen, brain) Indications ... course • Adjust antibiotics ... #criticalcare #diagnosis
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
starting amiodarone treatment ... pneumonitis Diagnosis ... macrophages Treatment ... #Pulmonary #diagnosis ... #management #Toxicology
Drug-Induced Prolonged QTc

QTc >500ms is an independent risk factor for developing Torsades des Pointes (TdP)
Drugs causing
Risperidone • Antibiotics ... Prolonged #QTc #Toxicity ... #Toxicology #Pharmacology ... #Diagnosis #prolongation
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
- Antithyroid medications ... - β-lactam antibiotics ... anemia) Labs: • Peripheral ... aplastic anemia Treatment ... oncology #hematology #diagnosis