38 results
Laboratory Testing in Hemolytic Anemia

Intravascular vs Extravascular Hemolysis
Reticulocytes
Unconjugated bilirubin
LDH
Peripheral smear
Haptoglobin
Urine hemosiderin
Urine hemoglobin
Carboxyhemoglobin

#Hemolytic #Anemia #Laboratory #Testing #workup
bilirubin LDH Peripheral ... smear Haptoglobin ... Laboratory #Testing #workup ... #diagnosis #hematology ... #hemolysis
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Hemolytic Anemias ... - Differential Diagnosis ... Reticulocytes • Abnormal peripheral ... smear Immune-mediated ... #Differential #Diagnosis
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood ... Smear Analysis ... Microangiopathic hemolytic ... #Blood #Smear # ... Analysis #hematology #microscopy
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... and laboratory diagnosis ... (black arrow) Peripheral ... smear changes are ... #Microscopy
How to distinguish a metamyelocyte from a band neutrophil.

- Kyle Bradley, MD
@KyleBradleyMD

#Clinical #Pathology #Microscopy #Blood #Smear
Clinical #Pathology #Microscopy ... #Blood #Smear # ... Peripheral #Metamyelocytes ... #Neutrophils #Comparison
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
Hemolytic Anemia ... - Differential Diagnosis ... Hereditary: • Peripheral ... blood smear + DAT ... #Differential #Diagnosis
Pancytopenia - Differential Diagnosis Algorithm
 • 12-13 g/dL,
 • ANC < 1800/uL,
 • platelet < 150,000/uL

Initial
/uL Initial Workup ... BMP, uric acid, peripheral ... smear, reticulocyte ... ↑ Destruction (hemolysis ... Algorithm #hematology #workup
Comparison of basophils and mast cells (in bone marrow).

#Basophils #MastCells #Pathology #Marrow #Smear #Microscopy #Comparison #Table
Comparison of basophils ... Pathology #Marrow #Smear ... #Microscopy #Comparison ... Table #Clinical #Diagnosis
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
Algorithm for workup ... observation of the peripheral ... thrombocytopenic purpura/hemolytic ... 2012, p 193 #Diagnosis
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
activity is the diagnostic ... available for rapid diagnosis ... the range of Peripheral ... blood smear - Shows ... #Workup #Hematology