22 results
hematology differential management vasculitis dermatology oncology signs intravascular rash thrombocytopenia workup activation algorithm aplastic arterial ascorbicacid bruising canimorsus capnocytophaga classification
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... OF NON-PALPABLE PURPURA ... - Hemolytic anemia ... Acute Infectious Purpura ... OF PALPABLE PURPURA
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... , Palpable purpura ... • Palpable purpura ... Vesicles overlying purpuric ... Henoch-Schönlein purpura
Scurvy (Vitamin C Deficiency) - Diagnosis and Management Vitamin C is required for hydroxylation of proline residues
Deficiency) - Diagnosis ... • Purpura • Perifollicular ... • Petechiae, purpura ... , or any other cause ... Henoch-Schonlein purpura
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... thrombocytopenic purpura ... Extravascular #Causes ... #hematology #anemia
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... Henoch-SchonIein Purpura ... #differential #diagnosis ... #algorithm #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... History of bleeding (petechiae ... pylori test (GI symptoms ... changes), high MCV anemia ... #hematology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
rash, Vasculitis, Purpura ... ) Blood (75%): Anemia ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
easy bruising to purpura ... mucosal bleeding (Petechial ... or purpuric rash ... with leukopenia, anemia ... #Rheumatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... Manifestations of DIC: • Petechiae ... • Purpura • ... Hemorrhagic bullae • Purpura ... #Coagulation #diagnosis
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Causes of Purpura ... thrombocytopenic purpura ... Henoch—Schönlein purpura ... - Scurvy #Purpura ... #peds #pediatrics
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