14 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... pain (20%) Renal disease ... ) Blood (75%): Anemia ... #erythematosus
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Findings: • Petechiae ... Maculopapular rash ... • Ulcerated, erythematous ... #dermatology #rash ... #diagnosis #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Manifestations: Malar rash ... • Immunologic Workup ... Evolution: Chronic disease ... Management #Summary #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... 3rd Decade Skin ... Non-autoimmune rheumatologic ... Seizures • Strokes Skin ... lymphopenia, low PLT • Anemia
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... 69% - Malar rash ... - Hemolytic anemia ... #Lupus #Erythematosus ... #differential #rheumatology
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
Differential Diagnosis Algorithm ... arthritis - with the skin ... Lupus Erythematosus ... like “butterfly rash ... Differential #Diagnosis #Algorithm
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
erythematosus ... mucosal bleeding (Petechial ... or purpuric rash ... with leukopenia, anemia ... #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
: erythematous nodules ... mucositis - Rash ... , such as systemic ... lupus erythematosus ... differential #diagnosis #rheumatology
Penicillin Allergy Pathway for Antibiotic Prescription in Patients With Penicillin Allergy
Mild Reaction - Itching, Minor rash
mucosal involvement, skin ... If infectious disease ... eosinophilia systemic ... syndrome, Hemolytic anemia ... #Prescription #algorithm
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
NPSLE rare, Malar rash ... months to years) Systemic ... Lupus Erythematosus ... Evolution: Chronic disease ... comparison #table #rheumatology