15 results
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
p450 CYP3A4 and P-glycoprotein ... to CYP3A4 and P-glycoprotein ... interactions with the P-glycoprotein ... CYP3A4 and P-glycoprotein ... #DOAC #CYP3A4 #Pglycoprotein
Amiodarone Toxicity and Monitoring

Tremor Ataxia 
Ocular neuritis 
Corneal Microdeposits 
Bradycardia 
Pulmonary fibrosis 
Hepatotoxicity 
Blue-gray skin
-3A4-2D6 and P-Glycoprotein
Azithromycin - since there has been a lot of noise around chloroquine/hydroxychloroquine, thought we can take
inhibitor of P-glycoprotein
Recommendations for initial management of Unstable Angina/NSTEMI

Flowchart for class I and class lla recommendations for initial
; GP Ilb/llla, glycoprotein
Azithromycin - since there has been a lot of noise around chloroquine/hydroxychloroquine, thought we can take
inhibitor of P-glycoprotein
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Anti-cardiolipin (aCl), ß2 glycoprotein
Antiphospholipid Syndrome (APS)
APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
aCL) • Anti-ß2 glycoprotein
Bleeding manifestations 
Petechiae are small, flat, red, discrete areas of skin bleeding that are typically <2
Willebrand factor Glycoprotein
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
oligodendrocyte glycoprotein
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
+ LAC, anti-β2-glycoprotein