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diagnosis lupus differential erythematosus systemic druginduced leukemia oncology signs symptoms treatment activation algorithm autoantibodies causes chronic cll comparison dil disorders
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... test, ANA (e.g., SLE ... changes), high MCV anemia ... Diagnosis #Causes #Workup ... #hematology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Systemic Lupus (SLE ... Photosensitivity, Butterfly rash ... ) Blood (75%): Anemia ... Leucopenia/lymphopenia, Thrombocytopenia ... symptoms #diagnosis #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Diagnosis and Management ... Manifestations: Malar rash ... • Immunologic Workup ... Usual therapeutic management ... #Summary #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
69% - Malar rash ... Neurological 12% - Thrombocytopenia ... - Hemolytic anemia ... Lupusreference #SLE ... #differential #rheumatology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... genotypes): SS, SC, SE ... Schistocytes, thrombocytopenia ... Diagnosis #Algorithm #workup ... #hematology #testing
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
NPSLE rare, Malar rash ... • Immunologic Workup ... • Immunologic Workup ... comparison #table #rheumatology ... #diagnosis #management
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook Presentation: • Plts ↓50% (nadir
Diagnosis and Management ... ♀, ↑Age, ESRD Pathophysiology ... Confirmatory test ↑Se ... Management: • ... #Treatment #Hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Petechial or purpuric rash ... erythematosus [SLE ... with leukopenia, anemia ... , and thrombocytopenia ... #Hematology #Rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... • Neutropenia, anemia ... , thrombocytopenia ... Leukemia #diagnosis #workup ... #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Granulocytic cells in all phases ... - infiltrates (anemia ... , thrombocytopenia ... lymphocytic lymphoma (SLL ... #Leukemia #Hematology
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