19 results
Diabetes Combination Tablets - Estimated A1c Lowering 
Metformin + DPP4 
• Janumet (metformin + sitagliptin) 
•
Diabetes Combination ... /ambcarerx #Diabetes ... Tablets #Oral #DM2 ... #Pharmacology # ... Pills #Endocrinology
Metformin - First Line Treatment for Diabetes Type 2
• Start with initial dose of 500 mg
Metformin - First ... Treatment for Diabetes ... form and consider using ... Indications #Titration #Pharmacology ... #Diabetes #DM2
Profiles of Antidiabetic Medications - AACE 2018 

#Antidiabetic #Medications #Profiles #SideEffects #Table #DecisionAid #Orals #DM2 #Diabetes
#SideEffects #Table ... DecisionAid #Orals #DM2 ... #Diabetes #Endocrinology ... #Pharmacology #
Diabetes Medications Summary Table
Insulin
Lifestyle modifications
Metformin
Sulfonylureas
GLP-1 receptor agonists - ↓ major adverse CV events
TZDs
DPP-4 inhibitors
SGLT2 inhibitors -
Diabetes Medications ... Summary Table ... modifications Metformin ... comparison #management #endocrinology ... #dm2
Metformin 
Current Renal Dose Adjustments due to Risk of Lactic Acidosis 
> 60 No adjustment 
45-60
Metformin Current ... Renal Dose Adjustments ... #Renal #Dosing ... #Dose #Pharmacology ... #Diabetes
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... oral agent • Does ... #Pharmacology # ... Summary #DM2 #diabetes ... #endocrinology
Algorithm for Metformin Prescribing and Dosing in CKD
Dose Initiation - Immediate release:
 • Initial 500 mg
Algorithm for Metformin ... Prescribing and Dosing ... #Metformin #Prescribing ... #Dosing #CKD #pharmacology ... #algorithm #diabetes
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
Normal and Renal Dosing ... Inhibitors #Renal #Dosing ... #Pharmacology # ... Management #Diabetes ... #DM2 #Endocrinology
Diabetes Mellitus Type 2 Inpatient Medication Guide

Classes: Biguanide, Sulfonylurea, TZD, DPP-4 inhibitor, GLP-1 receptor agonist, SGLT2i,
Adjust insulin dose ... #Mellitus #DM2 ... #Medications #pharmacology ... #comparison #table ... #endocrinology
Estimating the Total Daily Dose (TDD) of Insulin: Weight-Based Dosing
TDD in units of insulin = N
the Total Daily Dose ... : Weight-Based Dosing ... Weight #Based #pharmacology ... #endocrinology ... #diabetes #DM2