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management metformin insulin medications cardiology clinical comparison indications toxicity toxicology abortive acei acute ada algorithm anthracycline antidote arb based bloodsmear
Metformin - First Line Treatment for Diabetes Type 2 • Start with initial dose of 500 mg
Start with initial dose ... daily • Adjust dose ... Increase dose gradually ... highest dose tolerable ... #Diabetes #DM2
DPP4 Inhibitors - Normal and Renal Dosing Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
on the highest dose ... only use lower doses ... at the lowest dose ... #Pharmacology # ... #DM2 #Endocrinology
Stress Dose Steroids - Indications and Dosing SUPPRESSED HPA AXIS: prednisone >20mg/day x 3 weeks or more
Stress Dose Steroids ... Indications and Dosing ... #Endocrinology ... #Diagnosis #Management ... #Pharmacology
Diabetes Mellitus Type 2 Inpatient Medication Guide Classes: Biguanide, Sulfonylurea, TZD, DPP-4 inhibitor, GLP-1 receptor agonist, SGLT2i,
Calculate total daily dose ... Adjust insulin dose ... #Mellitus #DM2 ... #comparison #table ... #endocrinology
Estimating the Total Daily Dose (TDD) of Insulin: Weight-Based Dosing TDD in units of insulin = N
the Total Daily Dose ... : Weight-Based Dosing ... Weight #Based #pharmacology ... #endocrinology ... #diabetes #DM2
Metformin Pharmacology Summary Mechanisms of Action: • Suppresses gluconeogenesis by the liver • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... oral agent • Does ... #Metformin #Pharmacology ... #Summary #DM2 # ... diabetes #endocrinology
Therapeutic Drug Level Monitoring Carbamazepine - Sample immediately before next dose (trough) Clozapine - Sample immediately
-24 hours post dose ... 12 hours post dose ... - Intermittent dosing ... Ranges #Toxicology #Pharmacology ... #Diagnosis #Table
Metformin: Biguanide Metformin is the first-line medication for treatment of type 2 diabetes. It is very effective
medication for treatment ... of type 2 diabetes ... titrating the dose ... until at optimal dose ... #Metformin #Pharmacology
PDE5 inhibitors are usually the drugs of first choice for erectile dysfunction. PDE5 inhibitors enhance an erection that is
e.g. at lower doses ... #pharmacology #comparison ... #treatment #medications ... #dosing #drugs ... #table #pharmacotherapy
Management of Diabetes Mellitus in Patients With CKD 1. Monitor for changes in BP, serum creatinine, &
increase in the dose ... initiation of treatment ... an increase in dose ... ml/min per 1.73 m2 ... evidence-based pharmacologic
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