16 results
Metformin - First Line Treatment for Diabetes Type 2
• Start with initial dose of 500 mg
Start with initial dose ... daily • Adjust dose ... Increase dose gradually ... highest dose tolerable ... #Diabetes #DM2
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
on the highest dose ... only use lower doses ... at the lowest dose ... #Pharmacology # ... #DM2 #Endocrinology
Diabetes Mellitus Type 2 Inpatient Medication Guide

Classes: Biguanide, Sulfonylurea, TZD, DPP-4 inhibitor, GLP-1 receptor agonist, SGLT2i,
Calculate total daily dose ... Adjust insulin dose ... #Mellitus #DM2 ... #comparison #table ... #endocrinology
Estimating the Total Daily Dose (TDD) of Insulin: Weight-Based Dosing
TDD in units of insulin = N
the Total Daily Dose ... : Weight-Based Dosing ... Weight #Based #pharmacology ... #endocrinology ... #diabetes #DM2
Management of Diabetes Mellitus in Patients With CKD

1. Monitor for changes in BP, serum creatinine, &
increase in the dose ... initiation of treatment ... an increase in dose ... ml/min per 1.73 m2 ... evidence-based pharmacologic
PDE5 inhibitors are usually the drugs of first choice for erectile dysfunction.

PDE5 inhibitors enhance an erection that is
e.g. at lower doses ... #pharmacology #comparison ... #treatment #medications ... #dosing #drugs ... #table #pharmacotherapy
Insulin Calculations for Type 1 Diabetes 

Insulin-to-Carb Ratio (ICR) 500/TDD = #g of carbs covered by
calculations used in dosing ... mealtime insulin dose ... normal mealtime dose ... #DM1 #Pharmacology ... #Endocrinology
Rybelsus (oral semaglutide) - First Oral GLP-1 Agonist
Dosing:
3 mg daily x 30 days, then 7 mg
GLP-1 Agonist Dosing ... mg maintenance dose ... smaller starting dose ... the maintenance dose ... the maintenance dose
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
Does the patient ... Does the patient ... ACEi/ARBs - Hold ... Diabetes regimen ... revascularization does
Methotrexate Toxicology 

Intravenous leucovorin (folinic acid) treatment serves as a cofactor necessary for synthesis of thymidylate
(folinic acid) treatment ... Administer mg-to-mg dose ... • If ingested dose ... for at least 12 doses ... Toxicity #Management #Pharmacology