12 results
Back to the "10 Need to Know" series - Drug Therapeutic Target Levels. 

For lithium, target
vary depending on treatment ... Therapeutic range ... #Ranges #Toxicology ... #Pharmacology # ... Diagnosis #Table
Carbamazepine Toxicity

Carbamazepine (CBZ) is an antiepileptic drug commonly prescribed for seizure disorders, trigeminal neuralgia, neuropathic pain,
Carbamazepine Toxicity ... receptor agonism (at therapeutic ... Carbamazepine #Toxicity ... #Toxicology #Diagnosis ... SideEffects #Adverse #Pharmacology
Therapeutic Drug Level Monitoring 
Carbamazepine - Sample immediately before next dose (trough) 
Clozapine - Sample immediately
at anytime if toxicity ... - Intermittent dosing ... #Ranges #Toxicology ... #Pharmacology # ... Diagnosis #Table
Vancomycin Associated Acute Kidney Injury

 • Drug induced acute kidney injury is generally defined as a
Injury • Drug induced ... of vancomycin induced ... • Treatment includes ... Vancomycin #AKI #pharmacology ... #toxicology #diagnosis
Toxidromes Compared: Anticholinergic, Cholinergic, Opioid, Sympathomimetic, Sedative-Hypnotic

During your physical exam, look for evidence of some of
Sedative-Hypnotic During ... acute cholinergic toxicity ... Opioid toxicity ... #Diagnosis #Toxicology ... #Toxidromes #Comparison
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Toxicity - Summary ... occur at any time during ... treatment Statin-Induced ... Atorvastatin Diagnosis ... #myopathy #diagnosis
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
Amiodarone Induced ... starting amiodarone treatment ... of amiodarone-induced ... macrophages Treatment ... #management #Toxicology
Clozapine Toxicology
Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
Clozapine Toxicology ... patients who have treatment-resistant ... #Clozapine #Toxicology ... #Toxicity #Diagnosis ... #Pharmacology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... vs SLE Drug Induced ... : Usual therapeutic ... druginduced #lupus #sle #comparison ... #rheumatology #diagnosis
Drug-Induced Prolonged QTc

QTc >500ms is an independent risk factor for developing Torsades des Pointes (TdP)
Drugs causing
Drug-Induced Prolonged ... Kat_Watson #Drug #Induced ... Prolonged #QTc #Toxicity ... #Toxicology #Pharmacology ... #Diagnosis #prolongation