25 results
anemia algorithm oncology causes aiha blood cold comparison product reactions thrombocytosis acquired agglutinin atlas bloodcell calculation chronic classification cll common
Warm vs Cold Autoimmune Hemolytic Anemia Warm Autoimmune Hemolytic Anemia: • Mechanism: IgG and Complement-mediated • Etiology:
Hemolytic Anemia ... Hemolytic Anemia ... , Autoimmune disorder ... Hemolytic Anemia ... #hematology #diagnosis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
for Hemolysis - ... Intravascular Hemolysis ... Microangiopathic hemolytic ... lymphoproliferative disorders ... #diagnosis #hematology
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table Warm AIHA (48-70%) Cold AHA (16-32%) • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic ... Diagnosis Table ... #Hemolytic #Anemia ... #Diagnosis #Table ... #hematology
Autoimmune Hemolytic Anemia (AIHA) Treatment Warm AIHA: 1) Steroids - 1-2 mg/kg prednisone daily • Until
Autoimmune Hemolytic ... > 10, no more hemolysis ... esp if severe disease ... #Hemolytic #Anemia ... #management #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... elliptocytosis, autoimmune ... hemolysis) ARUPConsult ... @ARUPLabs #Hemolytic ... #workup #hematology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Diagnosis Congenital ... Diseases: • GATA2 ... Inflammatory and Autoimmune ... Antibody-mediated hemolysis ... #Diagnosis #Hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
-100): • Non-hemolytic ... anemia, CKD • Hemolytic ... - Extrinsic: Autoimmune ... Non-megaloblastic: Liver disease ... #Diagnosis #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Diagnosis: • hemolytic ... • Compensated hemolysis ... intravascular hemolysis ... #hemolytic #anemia ... #hematology #diagnosis
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Diagnosis Secondary ... iron deficiency, hemolysis ... Chronic inflammatory disorders ... (e.g. autoimmune ... #hematology #secondary
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
Splenomegaly - Differential ... Diagnosis Algorithm ... Myeloproliferative disorders ... Serum Sickness Hemolytic ... #Causes #Hematology
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