13 results
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Myelogenous Leukemia ... • Rheumatic disorders ... • Celiac disease ... effect following treatment ... #Causes #Hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
, coagulation disorders ... disorders CAUSES ... #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Blood Loss ... Deficiency • Aplastic ... Disease • Marrow ... Non-lmmune #Anemia #Classification ... #Causes #Hematology
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
the total white blood ... Myeloproliferative Disorders ... : • Chronic myeloid ... #Diagnosis #causes ... #hematology #basophils
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
promyelocytic leukemia ... ABO incompatible blood ... #diagnosis #causes ... #treatment #management ... #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... cells can indicate disease ... Pure red cell aplasia ... microglobulin Treatment ... #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... extramedullary disease ... Fibrinolysis & DIC ... #Hematology #Oncology ... #Diagnosis
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Headaches • Pale skin ... and petechiae Causes ... anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
of Hemostasis - Differential ... Diagnosis Framework ... gingivitis or gingival leukemic ... discern these causes ... #Diagnosis #Hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
caused by blood ... just beneath the skin ... • Anemia • Aplastic ... Marrow Failure • Chronic ... #hematology #oncology