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oncology differential chronic classification anemia aplastic cancer dic essential et hemeonc hemostasis hodgkins intravascular lymphoma lymphomas lymphoproliferative myelodysplasia myelodysplastic nonhodgkin
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Diagnosis Algorithm ... #Bleeding #Bruising ... #Algorithm #Causes ... #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... -> Invade Skin: ... Leukemia (CLL) ... #Hematology #Oncology ... #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... cells can indicate disease ... microglobulin Treatment ... #Leukemia #diagnosis ... workup #oncology #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Leukemia (CLL) ... in adults • Disorder ... chemotherapy for low-risk disease ... #hematology #hemeonc ... #diagnosis #management
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
promyelocytic leukemia ... • Severe Liver Disease ... #diagnosis #causes ... #treatment #management ... #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential Diagnosis ... Algorithm Hodgkin ... Treated Like Acute Leukemias ... - Amy Chung, MD ... pathophysiology #Hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
Bleeding and Bruising ... gingivitis or gingival leukemic ... liver failure, disseminated ... discern these causes ... #Hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Easy or unusual bruising ... just beneath the skin ... Myeloproliferative Disease ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Headaches • Pale skin ... and petechiae Causes ... virus (EBV) • Leukemia ... Anemia #oncology #hematology ... #diagnosis #management
Essential Thrombocythemia (ET) ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
PV, MDS, CML) Treatment ... • Treatment algorithms ... Thrombocythemia #ET #hematology ... #diagnosis #management ... #hematology
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