Pharyngitis diagnosis hematology management dermatology disease hepatology skin treatment table autoimmune workup cll causes hlh differential

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33 results

Causes of Thrombocytopenia - Differential Diagnosis Algorithm

Decreased Megakaryopoiesis
• Aplastic Anemia
• Toxic Damage (e.g.

- Differential ... Diagnosis Algorithm ... methotrexate) • Drugs Autoimmune ... ITP • SLE • CLL ... #Causes #Hematology

Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
1. Autoimmune Mediated Pancytopenia
2. Splenic Sequestration
Peripheral Destruction

Pancytopenia - Workup ... and Differential ... Diagnosis Algorithm ... Metastatic Disease ... #Hematology

Hemophagocytic Lymphohistiocytosis (HLH) Treatment
Primary HLH:
- HLH-94 Protocol
• Dexamethasone

with infection or autoimmune ... disease, treatment ... for refractory disease ... #Treatment #management ... #hematology

Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
• Mechanical Trauma (Microangiopathic hemolytic anemia):

Diagnostic Framework ... Extravascular Causes ... ) (e.g. lupus, CLL ... #differential # ... diagnosis #hematology

Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
• Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or

evaluation or workup ... glucocorticoid treatment ... symptoms (eg, skin ... Disorders #Algorithm #Differential ... #diagnosis #hematology

Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages

solid cancers • Autoimmune ... diseases: SLE++ ... Drugs, Unknown cause ... Treatment: • ... #management #treatment

Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
- Prior platelet count, family

Platelet Disorders - Differential ... Diagnosis and Workup ... not required in all ... #Diagnosis #Causes ... #Workup #hematology

Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to

age, however the disease ... Low or absent NK cell ... • Bicytopenia Treatment ... #management #treatment ... #hematology

Acquired von Willebrand Syndrome - Diagnosis and Management
• Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,

and Management ... thrombocythemia), Autoimmune ... disease • vWF ... #Management #treatment ... #hematology #differential

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