96 results
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
Related Disease Clinical ... pseudotumor 4 phenotypes ... diagnosis #management #phenotypes ... #workup #treatment ... #rheumatology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... fraction < 20% Differential ... hepatitis • Pulmonary ... diagnosis #management #treatment ... #rheumatology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Folate deficiency, Liver ... McLeod blood group phenotype ... stomatocytosis, Liver ... RBC #Morphology #differential ... #diagnosis #hematology
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
auricular papules Clinical ... prevalence of RP-ILD Phenotype ... Arthralgia/arthritis Phenotype ... muscle weakness Phenotype ... Dermatomyositis #rheumatology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... disease (diverse genotypes ... bartonella (oroya fever ... Hemolytic #Anemia #Differential ... Algorithm #workup #hematology
Lung Abscess
Microbiology:
 • Polymicrobial 
 • Anaerobes (most common) 
Clinical: 
 • Indolent symptoms that evolve
most common) Clinical ... to rnonths • Fever ... , hemoptysis Treatment ... Abscess #Diagnosis #Pulmonary ... #Clinical #CXR
Sarcoidosis 
Non-caseating granulomas (Composed of T-helper & inflammatory cells) 
Clinical:
 • Disease fatal in 10% of
inflammatory cells) Clinical ... Constitutional: Fever ... polyarthritis • Pulmonary ... exertion • Neurologic ... Symptoms #Signs #Pulmonary
Differential Diagnosis - Noninfectious Causes of Fever

CRITICAL DIAGNOSES:
 - Acute myocardial infarction
 - Pulmonary embolism or
Differential Diagnosis ... CRITICAL DIAGNOSES ... infarction - Pulmonary ... Transfusion reaction - Pulmonary ... Noninfectious #Causes #Differential
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
- Thalassemia, Liver ... Renal diseases, Liver ... PD deficiency, Pulmonary ... key #diagnosis #differential ... #hematology
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
Shock - Differential ... Insufficiency, Liver ... • Obstructive: Pulmonary ... Dehydration Shock Treatment ... criticalcare #algorithm #treatment