10 results
Evaluation abnormal liver tests in pregnancy
- Cholestatic Pattern
- Hepatocellular Pattern

#LFTs #transaminits #pregnancy #obgyn #obstetrics #hepatology #diagnosis
Evaluation abnormal ... Hepatocellular Pattern #LFTs ... obgyn #obstetrics #hepatology ... #diagnosis #differential ... #algorithm
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver Injury ... Levels: > 50x normal ... Patterns #Liver #Injury ... #hepatology #LFTs ... transaminitis #differential
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Diagnosis Algorithm ... Burak @kwburak #LFTs ... #diagnosis #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
dose dependent injury ... Chronic - ongoing ↑ LFTs ... Idiosyncratic #differential ... gastroenterology #algorithm ... gastroenterology #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
- Differential ... #Differential # ... Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Liver Enzymes - Differential ... Diagnosis Algorithm ... disease US — Normal ... • Others #LFTs ... #Hepatology #LiverEnzymes
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
Non-accidental Injury ... splenomegaly, abnormal ... neurology, back pain Haematology ... #Limping #NWB #Algorithm ... Pathway #Child #Peds
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
tests algorithm ... indicate the initial evaluation ... #LFTs #Abnormal ... #Algorithm #Hepatology ... Liver #Enzymes #Differential
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... - If both are normal ... chemistry #diagnosis #differential ... #Hepatology #transaminitis ... #LFTs #RValue #
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Diagnosis Algorithm ... function may be abnormal ... #diagnosis #algorithm ... #hepatology