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Table of Causes of Acute Liver Injury
#Diagnosis #Hepatology #Acute #Liver #Injury #Causes #Differential #Incidence #Table #Failure
of Acute Liver Injury ... #Diagnosis #Hepatology ... #Acute #Liver # ... Differential #Incidence ... #Table #Failure
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Liver Failure ( ... months without treatment ... Injury (DILI) ... #Hepatology #gastroenterology
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
Supportive with treatment ... liver failure ... Liver transplant ... Hepatobiliary #hepatology ... #hepatitis #differential
Indications for Albumin for Management of Cirrhosis
 • Large volume paracentesis (>5 liter) - 8g per
for Albumin for Management ... ascites removed • Acute ... kidney injury ( ... #Cirrhosis #treatment ... #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... liver failure rapidly ... → Multiorgan failure ... infiltration) Differential ... #Pregnancy #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Mixed - Check Acute ... Liver Failure ( ... injury < 26 weeks ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
injury (INR > 2 ... > 3 mg/dL) or acute ... liver failure ... #Indications #management ... #hepatology
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
pseudotumor 4 phenotypes ... hypergammaglobulinemia, ↑ acute ... Disease #diagnosis #management ... #phenotypes #workup ... #treatment #rheumatology
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
Shock - Differential ... Insufficiency, Liver ... Failure, Toxins ... Medications, Spinal Cord Injury ... #management
Babesia Microti - Clinical Features, Exam, Labs and Major Differential Diagnosis
Treatment: 1) Atovaquone and azithromycin 2)
Labs and Major Differential ... Diagnosis Treatment ... encephalopthy, acute ... liver failure) ... Babesia #Microti #Workup