47 results
Algorithm for the Evaluation and Management of Sickle Cell Crises
Clinical Manifestations and Management

#Diagnosis #Management #Hematology #SickleCell
of Sickle Cell Crises ... Clinical Manifestations ... and Management ... #Hematology #SickleCell ... Manifestations #Workup
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... PT, aPTT(liver disease ... bypass), LFT (liver disease ... #Workup #hematology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Summary • Epidemiology ... 40, F:M 9:1 • Clinical ... • Immunologic Workup ... Evolution: Chronic disease ... #Summary #rheumatology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... (diverse genotypes ... Hemolytic #Anemia #Differential ... Diagnosis #Algorithm #workup ... #hematology #testing
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... Clinical history ... #diagnosis #management ... #phenotypes #workup ... #treatment #rheumatology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... Clinical triad ... fraction < 20% Differential ... #diagnosis #management ... #treatment #rheumatology
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
auricular papules Clinical ... severity of the disease ... prevalence of RP-ILD Phenotype ... muscle weakness Phenotype ... Dermatomyositis #rheumatology
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group

< 5%
vasculitis - Diagnosis, causes ... and management ... cryoglobulinemia vasculitis Clinical ... with refractory disease ... Cryoglobulinemia #Vasculitis #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary ... #rheumatology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Cryofibrinogenemia Summary ... Diagnosis: • + Clinical ... cryoglobulins • Negative causes ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology