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diagnosis rheumatology signs differential syndrome temporal erythematosus giantcell lupus ra sjogrens sle systemic acutelimbischemia adult ali amputation aosd arthritis ascorbicacid
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations Risk Factors: - Unclear environmental triggers (may be viral, not
Cell (Temporal) Arteritis ... old; F>M Signs/Symptoms ... skin lesions ... #Pathophysiology ... #Vasculitis
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
, small-vessel vasculitis ... meningitis), MCC CNS symptoms ... inhibitors • Uveitis- Ophthalmology ... Syndrome #diagnosis #management ... #signs #symptoms
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Purpura, ischemic skin ... and often causes arthritis ... Glomerulonephritis, arthritis ... mucositis - Rash, arthritis ... Presentation - Systemic Symptoms
Highlighted Conditions With Arteritis or Periarteritis of the Coronaries Takayasu's arteritis: - Onset < 40 yrs -
yrs - Cranial symptoms ... Polyarteritis nodosa: - Skin ... multiplex ANCA vasculitis ... Leukocytoclastic vasculitis ... Behcet's disease
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Purpura, ischemic skin ... Presentation: Systemic Symptoms ... GCA (Giant Cell Arteritis ... • Progressive symptoms ... and often causes arthritis
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
Rheumatoid arthritis ... blood vessels (vasculitis ... interstitial lung disease ... RheumatoidArthritis #RA #pathophysiology ... #signs #symptoms
Kawasaki Disease: Clinical Findings Diagnostic Criteria - Fever and 4/5 of the following: • Conjunctivitis • Polymorphous
Kawasaki Disease ... : - Coronary Arteritis ... - Generalized Skin ... Criteria #Diagnosis #Pathophysiology ... #Vasculitis
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Butterfly rash, Vasculitis ... of hip (rare), Arthritis ... pain (20%) Renal disease ... erythematosus #signs #symptoms
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
other autoimmune diseases ... with systemic diseases ... like rheumatoid arthritis ... Xeroderma (Dry skin ... Sjogrens #Syndrome #Pathophysiology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic inflammatory vasculitis ... required due to skip ... required +/- prompt ophthalmology ... Temporal #Signs #Symptoms ... #Diagnosis #Management
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