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diagnosis rheumatology differential dermatology symptoms treatment clinical algorithm hematology cushings erythematosus hand hlh lupus lymphohistiocytosis oncology pharmacology physicalexam rash sjogrens
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... acquired forms of haemophagocytic ... A subset of hemophagocytic ... highly inflammatory disease ... #Diagnosis #Management
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
response to local skin ... retinal damage) • Skin ... test (this is a skin ... #diagnosis #management ... #signs #symptoms
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Hemophagocytic Lymphohistiocytosis ... Overwhelming clinical syndrome ... age, however the disease ... Diagnosis: HLH signs ... Lymphohistiocytosis #diagnosis #management
Erythematous Rashes - THE ALGORITHMIC APPROACH Characterized by diffuse redness of the skin due to capillary congestion, erythematous
redness of the skin ... staphylococcal scalded skin ... syndrome (SSS) ... includes Kawasaki disease ... and toxic shock syndrome
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
with more severe disease ... Associated with skin ... block • Sjogren syndrome ... polymyositis overlap syndrome ... #rheumatology #management
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
other autoimmune diseases ... with systemic diseases ... erythematosus (SLE) Signs ... Xeroderma (Dry skin ... Pathophysiology #Diagnosis #Signs
Characteristic clinical manifestations of Down syndrome Typical craniofacial appearance • Round face and flat
manifestations of Down syndrome ... folds (a fold of skin ... • Hirschsprung disease ... #Downs #Syndrome ... PhysicalExam #Features #Signs
Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:
Behcet's Syndrome ... for refractory disease ... Skin manifestations ... #Syndrome #Treatment ... #management #pharmacology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Sweet Syndrome ... ) is a skin condition ... inflamed or blistered skin ... with systemic disease ... Episcleritis Signs
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Purpura, ischemic skin ... Mucocutaneous lymph node syndrome ... VASCULITIS: • Behçet Syndrome ... • Cogan Syndrome ... purpura: strong sign
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