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diagnosis differential signs classification erythematosus lupus management sle vasculitis anterior arthritis autoimmune behcet clinical cryofibrinogenemia disease disorders lymphomas lymphoproliferative monoclonal
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features of Systemic ... defect (rare) Raynaud's ... Demyelinating syndromes ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... ulceration • Ocular ... meningitis), MCC CNS symptoms ... management #signs #symptoms ... #rheumatology #
Anterior Non-necrotizing Scleritis - Slit Lamp Ocular Examination This 57 yo WM reported to clinic complaining of
Scleritis - Slit Lamp Ocular ... and had no other symptoms ... patient was sent to rheumatology ... ophthalmology #physicalexam ... #rheumatology #
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 Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Cryofibrinogenemia Symptoms ... processes: • Systemic ... Arthralgias • Raynaud ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... site in lymphatic system ... with lymphatic system ... pattern of spread, B symptoms ... pathophysiology #Hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
clubbing Clarkson/Systemic ... neuropathy) • Systemic ... Hypergammaglobulinemic macular ... vascular beds-renal, retinal ... Paraproteinemias #Hematology
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
Arthritis - Signs and Symptoms ... • Ocular: Keratoconjunctivitis ... Rheumatoid vasculitis, Raynaud's ... Thrombocytosis, Felty's syndrome ... #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
ulcers, cutaneous, ocular ... • Cogan Syndrome ... : - Ocular inflammatory ... Symptoms (Sx) in ... differential #diagnosis #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
gland) biopsy • Ocular ... Central nervous system ... Nephrogenic DI Hematologic ... Cryoglobulinemia (4%-12%), Raynaud ... #Rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Symptoms (SX) in ... • Progressive symptoms ... ulcers, cutaneous, ocular ... : Ocular inflammatory ... Differential #Diagnosis #Rheumatology
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