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diagnosis erythematosus sle systemic differential activation behcet behcets cerebritis classification criteria dermatology macrophage mas monoclonal neurology oncology paraproteinemias polychondritis relapsing
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
ulceration • Ocular ... (panuveitis, retinal ... basal ganglia, CNS ... #diagnosis #management ... signs #symptoms #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Demyelinating Syndrome ... Cerebrovascular Disease ... #neurology #rheumatology ... cerebritis #diagnosis #management
Behcet's Syndrome - Diagnosis Diagnostic Criteria for Behget's Syndrome (International Study Group for Behget's Disease): • Recurrent,
Behcet's Syndrome ... or retinal vasculitis ... Abnormal pathergy test ... , retinal vasculitis ... #criteria #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Initial screening test ... #Systemic #Lupus ... Summary #diagnosis #rheumatology ... #management
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... Scleromyxedema (CNS ... to cold IgG • Lupus ... vascular beds-renal, retinal ... Paraproteinemias #Hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Erythematous, macular ... Non-autoimmune rheumatologic ... Malignancy (e.g. hematologic ... and CNS • Headache ... Erythematosus #Diagnosis #Rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Systemic lupus ... nervous system (CNS ... Liver function tests ... #Diagnosis #Management ... #Hematology #Rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
gland) biopsy • Ocular ... Nephrogenic DI Hematologic ... phenomenon (16%) MSK ... #Rheumatology # ... Diagnosis #Management
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Others: • Lupus ... • Cogan Syndrome ... such as systemic lupus ... retinopathy Lab Tests ... differential #diagnosis #rheumatology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
sites such as the collar ... blockers had the best ... osteoarticular and skin disease ... #Rheumatology # ... diagnosis #management
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