25 results
Behcet's Syndrome - Diagnosis
Diagnostic Criteria for Behget's Syndrome (International Study Group for Behget's Disease):
 • Recurrent,
or retinal vasculitis ... Abnormal pathergy test ... , retinal vasculitis ... and peripheral vascular ... #criteria #rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
ulceration • Ocular ... (panuveitis, retinal ... and diplopia) • Vascular ... : Giant retinal ... signs #symptoms #rheumatology
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... refractory lesions Ocular ... immunosuppressive meds) Vascular ... #Syndrome #Treatment ... #pharmacology #rheumatology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Membrane): - Autoimmune ... Drug-associated, PCH, Evans Syndrome ... , Drugs, Liver Disease ... Laboratory Tests ... Differential #Diagnosis #hematology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Hyperviscosity, - Vascular ... associated with autoimmune ... thrombi including retinal ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Heavy Chain disease ... Hypergammaglobulinemic macular ... (Thrombosis in vascular ... beds-renal, retinal ... Paraproteinemias #Hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Erythematous, macular ... • Non-autoimmune ... rheumatologic diseases ... deficiencies • Autoimmune ... Erythematosus #Diagnosis #Rheumatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral infection, autoimmune ... • Diagnostic Test ... Donath-Landsteiner test ... hemolytic #anemia #hematology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
be any age) Autoimmune ... gland) biopsy • Ocular ... Nephrogenic DI Hematologic ... phenomenon (16%) MSK ... #Rheumatology #
Facial Swelling - Differential Diagnosis Framework for Facial Edema

Infectious:
	• Dental abscess
	• Ludwig's angina
	• Vincent's angina
	• Cellulitis
	•
puffy tumor Autoimmune ... Adult-onset Still's disease ... Trauma: • Ocular ... Myxedema coma Vascular ... Differential #Diagnosis #PhysicalExam