17 results
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
/ Symptoms / Complications ... partial retinal red reflex ... Retinoblastoma #pathophysiology ... ophthalmology #diagnosis ... #signs #symptoms
Diagram of different types of bone tumors that can occur around the knee on XRay -
• Giant cell tumor ... phase • Paget disease ... blade of grass sign ... #Tumors #Diagnosis ... Radiology #XRay #msk
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Weakness, Incr CK • Bone ... Erythematosus #SLE #MSK ... #pathophysiology ... #signs #symptoms ... #diagnosis
Diagram of different types of bone tumors that can occur around the knee on XRay
Age <
• Giant cell tumor ... phase • Paget disease ... blade of grass sign ... #Differential #Diagnosis ... Radiology #XRay #MSK
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
tear a portion of bone ... /Symptoms/Complications ... FemoralHead #Fractures #msk ... #diagnosis #pathophysiology ... #signs #symptoms
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Pott's Disease in ... cases Clinical Signs ... numbness, decreased reflexes ... Pathophysiology ... of bacilli to bone
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Alzheimer’s Disease ... / Symptoms / Complications ... seizure, primitive reflexes ... AlzheimersDisease #Dementia #pathophysiology ... #geriatrics #diagnosis
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
Differential Diagnosis ... • Mutism Pathophysiology ... myoclonic movements, tremors ... • Examine for signs ... caseyalbin #PhysicalExam
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
/ Symptoms / Complications ... of normal leg reflexes ... CaudaEquina #Syndrome #MSK ... #pathophysiology ... #diagnosis #symptoms
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
Paget’s Disease: ... Complications ... formation MSK ... PagetsDisease #pathophysiology ... #diagnosis #signs