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differential hematology management rheumatology oncology causes neurology signs vasculitis clinical infectiousdiseases treatment algorithm classification hemeonc leukemia ophthalmology rash secondary skin
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
ALL Symptoms: ... extramedullary disease ... lysis syndrome: ... ) CLL Symptoms: ... #Oncology #Diagnosis
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
e.g., HIV), EBV infection ... Etiology: - Infections ... extranodal) - Tumor ... Differential Diagnosis ... #differential #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... lymphoid malignancy (CLL ... malignancies -> CLL ... hemolytic #anemia #hematology ... #diagnosis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... ) - HELLP syndrome ... Hemolytic uremic syndrome ... ) (e.g. lupus, CLL ... #hematology #anemia
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... weeks without infection ... Diagnosis: • ... cells can indicate disease ... • Richter’s Syndrome
Clinical Manifestations of Serotonin Syndrome • Ophthalmologic: Mydriasis, Ocular clonus (slow horizontal movements) • Gastrointestinal: Diarrhea,
Ophthalmologic: Mydriasis, Ocular ... sounds, RUQ pain • Dermatologic ... Status (agitated), Tremor ... #Symptoms #spectrum ... #signs #diagnosis
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
Visual or auditory symptoms ... conjunction with symptoms ... and less common diseases ... • Lyme disease ... nasal squamous cell
Facial Swelling - Differential Diagnosis Framework for Facial Edema Infectious: • Dental abscess • Ludwig's angina • Vincent's angina • Cellulitis •
Facial Edema Infectious ... Preeclampsia Dermatologic ... Trauma: • Ocular ... - CLL Others ... #PhysicalExam
Central Distribution, Febrile / Ill: - Viral Exanthem - Lyme Disease (erythema migrans) Central Distribution,
Exanthem - Lyme Disease ... Stevens-Johnson Syndrome ... Maculopapular #Macular ... Rash #Algorithm #Diagnosis ... #Dermatology #Skin
Ear Pain (Otalgia) - Differential Diagnosis Framework Primary Otalgia - Pain that originates from the ear
- Differential Diagnosis ... Basal/squamous cell ... the following symptoms ... • Associated symptoms ... vision or black spots
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