10 results
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
) - Diagnosis and ... - CRP: Usually normal ... life-threatening • Treatment ... Evolution: Chronic disease ... Management #Summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Activation of CD8 ... : SLE+++, Adult-onset ... Still disease, ... Drugs, Unknown cause ... #summary #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Discontinuation of causal ... Evolution: Chronic disease ... #comparison #table ... #rheumatology # ... diagnosis #management
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
sequestration and activation ... without other cause ... Transfusion #Reactions #hematology ... #diagnosis #comparison ... #table
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
erythematosus [SLE ... Treatment: • Corticosteroids ... #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• Severe Liver Disease ... Treat primary cause ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Hypocomplementemia • Can cause ... Nephrogenic DI Hematologic ... Adenocarcinoma Treatment ... Sjogrens #Syndrome #Rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
- Differential Diagnosis ... , such as SLE, atherosclerotic ... fluid (CSF) is abnormal ... tract, and often causes ... #Rheumatology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
lymph node biopsy (diagnostic ... number of sites of disease ... Hodgkin Lymphoma Treatment ... #lymphoma #diagnosis ... classification #hematology
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
exclude other causes ... cardiomyopathy • Pulmonary ... sx overlap with normal ... orthopnea, PND, LE ... management #cardiology #treatment