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oncology syndrome aplastic chronic lymphocytic mds algorithm apml arteritis classification differentiation erythematosus gca giantcell hemeonc hodgkins lupus lymphoma myelodysplasia signs
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
cytopenias (usually anemia ... risk-stratification • Risks: infection ... transformation to acute leukemia ... #Management #treatment ... #hematology #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
- infiltrates (anemia ... lymphoid organs When Cancer ... ) CLL Symptoms: ... #Hematology #Oncology ... #Diagnosis
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Script Signs and symptoms ... : • Recurrent infections ... to MDS or acute leukemia ... #diagnosis #management ... #treatment #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
- Summary Cancer ... with no early symptoms ... weeks without infection ... • Neutropenia, anemia ... #oncology #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Complications: 1) Infection ... uw_IMresidency #CLL ... #oncology #hematology ... #hemeonc #diagnosis ... #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... Leukemia • Idiopathic ... • Parvovirus infection ... #Syndromes #diagnosis ... #hematology #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
virus (EBV) • Leukemia ... Treatment: ... • Improve the symptoms ... #oncology #hematology ... #diagnosis #management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
• Induce blast cell ... Imaging: CXR- pulmonary ... : >3 symptoms, or ... : Infection (sepsis ... #management #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... ingestion • B symptoms ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
acute myeloid leukemia ... median age at diagnosis ... cardiovascular or pulmonary ... disease tolerate anemia ... #algorithm #hematology
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