43 results
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
GrepMed Handbook Clinical ... malignancy Pathophysiology ... - GH-secreting pituitary ... • Pituitary ... Endocrinology #Treatment #Pathophysiology
Clinical Effects of Large and Small Pituitary Tumours
Local complications - Headache, Visual field defect, Disconnection hyperprolactinaemia,
Clinical Effects ... Large and Small Pituitary ... infarction/expansion (pituitary ... Hypogonadism • Acromegaly ... and polyuria #Pituitary
Primary vs Secondary Adrenal Insufficiency - Pathophysiology
Primary AI = adrenal glands themselves are the problem. This
Primary vs Secondary ... Insufficiency - Pathophysiology ... Primary AI = adrenal ... Secondary AI = the pituitary ... Insufficiency #Pathophysiology
Primary Hyperthyroidism - Pathogenesis and Clinical Findings

Note: Although rare, gestational diseases can lead to thyrotoxicosis due
Primary Hyperthyroidism ... Pathogenesis and Clinical ... production by the pituitary ... Pretibial myxedema #Primary ... endocrinology #pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
Pathogenesis and clinical ... findings • Acromegaly ... share the same pathophysiology ... rare causes of acromegaly ... endocrinology #pathophysiology
Acromegaly in patient with a pituitary adenoma #acromegaly #pituitary #adenoma #GnRH #Hand #PhysicalExam #clinical #photo
Acromegaly in patient ... with a pituitary ... adenoma #acromegaly ... #pituitary #adenoma ... #PhysicalExam #clinical
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
- Giantism or acromegaly ... endocrinology #pathophysiology ... #pituitary
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
Pituitary Mass Effects ... Pathogenesis and Clinical ... Findings • Pituitary ... Pituitary adenomas ... mnemonic #GLFTAP #pathophysiology
Approach to Thyroid Function Tests in the Evaluation of Hyperthyroidism
 • Low TSH, Low normal T4
of pregnancy, critical ... high T4 +/- T3 → Primary ... Hyperthyroidism → MRI Pituitary
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
Primary Sjogren’ ... Pathogenesis and Clinical ... Findings • Primary ... processes like primary ... Sjogrens #Syndrome #Pathophysiology