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diagnosis management sle systemic classification differential ana anca antibodies antibody antineutrophil antinuclear associated comparison cryoglobulinemia cryoglobulins diseases druginduced glomerulonephritis gn
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... and Management Summary ... nephritis, NPSLE ... life-threatening • Treatment ... #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
ANCA-associated vasculitis ... Non-autoimmune rheumatologic ... • Mesenteric vasculitis ... APLA/LAC: • Renal ... #Diagnosis #Rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... - Summary Antinuclear ... severe disease & renal ... severe disease Treatment ... #rheumatology #
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
) • Systemic lupus ... erythematosus ... ANCA-Associated Vasculitis ... vasculitis - MPO ... antibodies #diagnosis #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
constitutional symptoms • Treatment ... Erythematosus ( ... nephritis, NPSLE ... life-threatening • Treatment ... comparison #table #rheumatology
Staphylococcus-associated GlomeruloNephritis - Diagnosis and Management Summary CLINICAL • Nephritic syndrome (Casts) • Marked proteinuria (may be
and Management Summary ... CLINICAL • Nephritic ... syndrome (Casts ... Leukocyturia • Vasculitic ... deposits common TREATMENT
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... inflammation Others: • Lupus ... such as systemic lupus ... erythematosus, ... differential #diagnosis #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Cryoglobulinemia Summary ... • They can cause ... (e.g. systemic lupus ... erythematosus ( ... classification #rheumatology
Secondary Causes of Hyperlipidemia Nunerous secondary causes of hyperlipidemia exist; screening for the presence of these underlying
mellitus, Chronic renal ... Glucocorticoid treatment ... hepatitis, Systemic lupus ... erythematosus ... Hypothyroidism, Nephrotic
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
) • Cutaneous vasculitis ... • Interstitial nephritis ... : 2% Systemic Vasculitis ... Adenocarcinoma Treatment ... Sjogrens #Syndrome #Rheumatology
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