11 results
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... salmon-colored maculopapular ... rash, arthritis ... BrighamChiefs #AdultOnset ... rheumatology #diagnosis #management
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... arthritis, Skin rash ... Prunelle Getten #AdultOnset ... #diagnosis #management ... #treatment #rheumatology
Adult Onset Still's Disease - Yamaguchi Criteria
Major criteria:
 - Fever >= 39C lasting >= 1 weeks
Adult Onset Still's ... - Typical skin rash ... : maculopapular, ... non-pruritic, salmon-pink rash ... polyarteritis nodosa #AdultOnset
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... nonpruritic macular or maculopapular ... Treatment - Mild ... : NSAIDS Treatment ... #rheumatology #management
Streptococcal Toxic Shock Syndrome (STSS)
Complication of invasive GAS disease characterized by shock & MOF → occurs
of invasive GAS disease ... blood) • Early onset ... erythematous macular rash ... necrosis STSS Treatment ... #management #diagnosis
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
extensive skin rash ... • Maculopapular ... withdrawal • Mild disease ... : symptomatic treatment ... • Severe disease
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
/sx urticaria, maculopapular ... rash, pruritis, ... resembles ARDS, onset ... Borrellia (Lyme disease ... Transfusion #diagnosis #management
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
/sx urticaria, maculopapular ... rash, pruritis, ... resembles ARDS, onset ... Borrellia (Lyme disease ... Transfusions #diagnosis #management
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
worsening of that disease ... initiation and onset ... pericarditis, peritoneal disease ... meningitis • Guidelines ... Differential #Diagnosis #Management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
sJIA) • Adult-onset ... Still disease ... Petechial or purpuric rash ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management