13 results
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
receptor] • Thrombocytopenia ... MYH9-Related Disorder ... #Defects #comparison ... #table #differential ... #diagnosis #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
and Platelet Disorders ... - Differential Diagnosis ... and Workup History ... #Platelet #Disorders ... #hematology
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
Platelet disorders ... aggregation to all ... Gplb receptor • Thrombcytopenia ... #disorders #hematology ... #differential #diagnosis
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... hemorrhagic skin lesions ... inflammation • Thrombocytopenia ... #Differential #Diagnosis ... #hematology #rheumatology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... Liver tests, Low Platelets ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison ... #Table
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... Liver tests, Low Platelets ... AFLP #obstetrics #hematology ... #diagnosis #table ... #comparison
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
with or without platelet ... Schistocytes, thrombocytopenia ... Consider RBC membrane disorder ... #Algorithm #workup ... #hematology #testing
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential Diagnosis ... hemostasis: - Thrombocytopenia ... - Abnormal platelet ... Vasculitis - Collagen disorders ... deficiency Work
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... count (thrombocytopenia ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
patients Skin lesions ... doi: 10.1111/all ... Cold #Urticaria #diagnosis ... #rheumatology # ... comparison #table