26 results
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Scl70 (in some cases ... Smith, Sm/RNP, Scl ... Scl100, Th/To, Scl ... #differential # ... diagnosis #rheumatology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
- Differential ... Diagnosis Algorithm ... Chronic Bleed - Any ... #Classification ... #Causes #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential ... Diagnosis and Workup ... (e.g., SLE), anti-phospholipid ... changes), high MCV anemia ... #Diagnosis #Causes
Antinuclear Antibody Testing - Nuclear Patterns
Homogeneous pattern: 
 • SLE, SSc, AIH, JIA
 • dsDNA, chromatin,
: • SLE, SSc, ... : • SjS, SLE, DM ... Smith, Sm/RNP, Scl ... #differential # ... diagnosis #rheumatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... - Hemolytic anemia ... Associated - SLE ... #Diagnosis #hematology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
- Hemolytic anemia ... Auto-Antibodies: - ANA ... ) 30-45% Differential ... Diagnosis and Lupus ... #rheumatology
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Abnormality • SLE ... Iron deficiency anemia ... #Differential # ... Diagnosis #Algorithm ... #causes
Arthritis of the Hand - Arthritis Patterns

Osteoarthritis:
• Osteoarthritis of the hand usually involves the DIP and
Hand - Arthritis Patterns ... ulnar deviation • SLE ... PsA, Sickle cell anemia ... #hand #diagnosis ... #rheumatology #
Clinical Classification of Pulmonary Hypertension

1. Pulmonary arterial hypertension from pulmonary vasculopathy
Idiopathic pulmonary arterial hypertension
Heritable gene mutations
Chronic hemolytic anemia ... obstructive pattern ... multifactorial mechanisms Hematologic ... #Diagnosis #Differential ... #Causes
Papulosquamous Skin Rash - Differential Diagnosis Algorithm
Erythrematous or violaceous papules & plaques with overlying scale
 •
Diagnosis Algorithm ... Christmas tree pattern ... Papulosquamous #SkinRash ... #dermatology #Differential ... #causes