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diagnosis syndrome treatment hemophagocytic lymphohistiocytosis oncology barre hemeonc neurology apml classification differentiation disorders gbs guillainbarre heparin hit hodgkins induced leukostasis
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
) Pathophysiology ... Triggering factor (infection ... : • Infections ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Pathophysiology ... response preceding infection ... complete paralysis of all ... Syndrome #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) Treatment Primary HLH: - HLH-94 Protocol • Dexamethasone
Treatment Primary HLH ... trigger • Almost all ... associated with infection ... #Treatment #management ... #hematology
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... complete paralysis of all ... the underlying pathophysiology ... SinaiBmoreIMRes #GBS #Guillain ... Syndrome #diagnosis #management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... History of EBV infection ... LN on alcohol ingestion ... classification #hematology ... #oncology #management
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
• In all patients ... Triggers: ▪ Infections ... Pathophysiology ... underlying trigger: Infections ... #Hematology #HemeOnc
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... have fever - ACS ... ischemia, bowel infarction ... TLS #diagnosis #management ... #hematology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook Presentation: • Plts ↓50% (nadir
Diagnosis and Management ... skin necrosis (at injection ... ♀, ↑Age, ESRD Pathophysiology ... D/c all heparin ... #Treatment #Hematology
Post-Transplantation Lymphoproliferative Disorders (PTLD) Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
accounts for 21% of all ... , intensity of induction ... haploidentical>unrelated>HLA ... symptoms, unexplained hematologic ... oncology #diagnosis #management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Incidence: common in APL ... ATRA treatment Pathophysiology ... Differential Diagnosis: Infection ... APML #diagnosis #management ... #hematology #oncology
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